We know fatigue can cause drowsiness and so can the other so my best guess is drowsiness
The interval between values is not interpretable in an ordinal measure. In interval measurement the distance between attributes does have meaning. For example, when we measure temperature (in Fahrenheit), the distance from 30-40 is same as distance from 70-80. The interval between values is interpretable.
I would say tylenol because it was used as a pain killer back then
The correct answer is drug antagonism