Many indigenous cultures lost their land.It showed that a small country can make a big impact.
The short answer is: "to a great extent". The entire plan of the Federalists was to create a strong central government instead of having many autonomous states. Of course this occasionally went against national unity in the sense that some people were opposed to this plan, but in general they favored unity.
I believe the answer is the United States.
The Declaration of Independence says that the American colonists are absolved from all ties and allegiances to the British Crown, since they argue the British have acted tyrannically. <span />