The correct answer is that "the T cell enters a state of anergy".
The activation of T cells requires two signals: (1) antigen specific signal presented by an antigen presenting cell (either a macrophage or a dendritic cell) that activates t cell receptors and (2) co-stimulatory signals that is not antigen specific but rather found in the plasma membrane of the antigen presenting cell (i.e. CD28). In the absence of a co-stimulatory signal, the t cell will enter a state of anergy or the inability to produce an immune response toward an offending antigen.
The integumentary system is the skin. Skin protects the inner organs from Bactria. Essentially the skin is a wall protecting against the outside world. It doesn't really release anything but is just there for protection.
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