Question

An article's subject may influence _____.

Answer 1

C) who reads it. 
The audience is determined by the subject, and who reads it is the audience. Hope this helps!

Answer 2

The best and most correct answer among the choices provided by your question is all of the above which is the fifth choice.
An article's subject may influence:

when it is published
whether is effectively received
who reads it
what the writer intends to do for the reader

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