Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
Answer:
A blizzard can form when warm air combines with a high pressure system.
Explanation:
A high pressure zone is defined by cold air mass that has higher density than surrounding air mass. Therefore when a warm air current blows towards the high pressure system, the warm air mass rises over the cold air mass of the high pressure system.
The warm air begins to cool at the front between the cold air mass and warm air mass. Usually for a blizzard to occur the cold air mass is usually below freezing point temperatures. Therefore the moisture in the warm air cools and freezes into snowflakes. This is why the winds of a blizzard are accompanied by snowflakes akin to a winter storm.
Lean More:
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By which organisms that contain the pigment chlorophyll convert light energy into chemical energy which can be stored in the molecular bonds of organic molecules.