Answer:
How are gametes different from all of the other cells that make up an organism.
Reasons are not far fetched as result of fertilization occurrence after mating which leads to having multiple cells in a gamete. The fusion of male and female organism leads to formation of gametes which consists of multiple cells
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by designing a drug with steric effects on BCR-ABL1
Explanation:
Chronic myeloid leukemia (CML) is a type of cancer that affects the bone marrow and blood cells. CML is characterized by the formation of the Philadelphia chromosome, a product of a reciprocal translocation between chromosomes 9 and 22. As a consequence of this translocation, an oncoprotein tyrosine kinase called BCR-ABL1 is formed. This protein (BCR-ABL1) is responsible for 95% of all CMLs. In this case, it is possible to inhibit BCR-ABL1 (and thus inhibit CML cell proliferation) by using a kinase inhibitor. Kinase inhibitors are drugs that inhibit kinase function by preferentially binding to the inactive conformation of the target enzyme. These proteins are used to treat cancer by blocking a functional site on the kinase, thereby inhibiting its function. Moreover, it is known that steric effects alter the mode and rate by which a drug interacts with a given target. In this case, a small molecule with steric effects on BCR-ABL1, i.e., capable of altering the shape (conformation) and reactivity of BCR-ABL1, might also be used to selectively inhibit BCR-ABL1.
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The moons of Saturn are numerous and diverse, ranging from tiny moonlets only tens of meters across to enormous Titan, which is larger than the planet Mercury. Saturn has 82 moons with confirmed orbits that are not embedded in its rings of which only 13 have diameters greater than 50 kilometers as well as dense rings that contain millions of embedded moonlets and innumerable smaller ring particles.Seven Saturnian moons are large enough to have collapsed into a relaxed, ellipsoidal shape, though only one or two of those, Titan and possibly Rhea, are currently in hydrostatic equilibrium. Particularly notable among Saturn's moons are Titan, the second-largest moon in the Solar System (after Jupiter's Ganymede), with a nitrogen-rich Earth-like atmosphere and a landscape featuring dry river networks and hydrocarbon lakes Enceladus, which emits jets of gas and dust from its south-polar region,and Iapetus, with its contrasting black and white hemispheres.
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Please give me a better understanding
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Saturated fatty acids have all of their carbon atoms bonded to hydrogen atoms.The lipids containing saturated fatty acid are solid at room temperature
Unsaturated fatty acids have some of their carbon atoms double bonded in place of hydrogen atoms.The lipids containing unsaturated fatty acids are liquid at room temprature.
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