The Chargaff's rule state that in DNA, equality often exist in quantity between the bases A and T and between the bases G and C. According to Chargaff's data, adenine must pair with thymine and guanine must pair with cytosine.
- Chargaff's gave rules for the pairing of bases. The rule is made up of base pairs in the DNA double helix.
He stated that there is a relation of A with T. The Pyrimidine Thymine (T) will always pairs with the Purine Adenine (A)
and also there is a relation of C with G and thus the Purine Guanine (G) always pair with the Pyrimidine Cytosine (C)
Erwin Chargaff was an Austrian-American biochemist. He lived from 1905-2002. It was at Columbia University that he discovered this rule.
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