Question

Explain how an SNP may produce a restriction fragment length polymorphism (RFLP).

Answer 1

Answer:Single nucleotide polymorphisms or SNPs (pronounced "snips") are DNA

sequence variations that occur when a single nucleotide (A,T,C, or G) in the

genome sequence is altered (point mutation).

SNPs do not cause disease, but they can help determine the likelihood that someone will develop a particular disease.

Because single base mutations can either create additional restriction sites or destroy pre-existing sites, DNA preparations from different individuals frequently exhibit different patterns of size distribution of restriction fragments that hybridize with a particular probe. These differences are called

restriction fragment length polymorphisms (RFLPs).

Explanation: