Question

Sickle cell anemia is a monogenic disorder in which the body produces abnormally shaped red blood cells. Sickle cell anemia is inherited in an autosomal recessive pattern. A person who is a carrier for this disease typically do not show signs and symptoms of the condition. Two cousins in Bangladesh got married and had kids without being aware that sickle cell disease runs in their family. Laboratory testing later showed that both partners were carriers for the sickle cell mutation. If this couple decides to have children, What is the chance (probability) that their children will also be carriers of the sickle cell disease?

Answer 1

Answer:

there's a ½ or 50% chance of their children will also be carriers of the sickle cell disease.

Explanation:

let IA = normal and IS =sickle cell

since both parents are carriers so it would be IAIS x IAIS

IAIS x IAIS

1 IAIA, 2 IAIS, 1 ISIS