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Masja [62]
3 years ago
11

Why do children with junctional epidermolysis bullosa have fragile skin

Biology
1 answer:
Kazeer [188]3 years ago
4 0
Because of a mutation in the COL7A1 gene which is the gene that provides the body with instructions for making the protein that form the pieces of a larger protein that makes collagen
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Which are the possible genotype combinations for their offspring? Check all that apply
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There are four possible combinations of gametes for the AaBb parent. Half of the gametes get a dominant A and a dominant B allele; the other half of the gametes get a recessive a and a recessive b allele. Both parents produce 25% each of AB, Ab, aB, and ab.

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3 years ago
In addition to E. coli, a risk factor for development of pyelonephritis is: a. urinary retention and reflux. b. nephrotic syndro
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Answer:

One of the factors for the development of pyelonephritis, in addition to E. coli, is urinary retention and reflux (option a).

Explanation:

Pyelonephritis is an infection of the upper urinary tract caused by bacteria in the urine, such as Escherichia coli.

Under normal conditions, urine in the urinary bladder is aseptic, that is, without bacteria.  The presence of bacteria in the urine indicates a urinary infection.

Urinary retention is the limitation of the expulsion of urine from the bladder. This promotes:

  • <em>An increase in the amount of bacteria present in the bladder. </em>
  • <em>The pressure generated by urine retention causes the bladder to generate a retrograde flow - reflow - towards the ureters, leading the bacteria to the kidneys. </em>

The result of urinary retention and reflux - when bacteria are present - is an infection in the upper urinary tract, called pyelonephritis.

Learn more:

Urinary tract infection brainly.com/question/4756206

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