The exchange that most affected the indigenous people was the one of diseases. Native Americans hadn't encounter the diseases the European brought before, so they hadn't develop immunity to them. This is the major reason of the large death of Native Americans, besides the war between them and the brutality of the Europeans.
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area 3 that's how we got ohio
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have a good day
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you can delete your other questions on this topic, i gotchu :D
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Torah - Judaism
Qu’ran - Islam
New Testament- Christianity
