There are 2 main processes to test tablet hardness: compression testing and 3 point bend testing. For compression testing, the analyst generally aligns the tablet in a repeatable way, and the tablet is squeezed between a fixed and a moving jaw. The first machines continually applied force with a spring and screw thread until the tablet started to break. When the tablet fractured, the hardness was read with a sliding scale.
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most people with down syndrome can function to some degree in society
Answer: Middle East respiratory syndrome coronavirus (MERS-CoV) is a lethal zoonosis that causes death in 35·7% of cases. As of Feb 28, 2018, 2182 cases of MERS-CoV infection (with 779 deaths) in 27 countries were reported to WHO worldwide.
Explanation:
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Despite minimal evidence of effectiveness, pancreatic enzyme supplementation is frequently used to relieve pain in people with chronic pancreatitis.
Comparing pancreatic enzyme supplementation to placebo, no improvement in discomfort was seen. The only trial that used enzymes without an enteric coating did indicate a decrease in pain score. In both analyses, there was a significant amount of study heterogeneity. A random model meta-analysis of three studies found no evidence of a difference between the periods of administering pancreatic enzyme supplementation versus placebo in the mean daily pain score (mean difference: 0.09 (1.57-1.39), p=0.91) or average weekly analgesic consumption (mean difference: 0.30 (2.37-1.77), p=0.77). Given their high cost and probable adverse effects, pancreatic enzyme supplements shouldn't be recommended only for treating abdominal pain in people with chronic pancreatitis.
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