Isabella d'Este was a Renaissance figure who was a valued advisor to her husband, the ruler of Mantua, and took charge of the court after he retired.
The best option from the list would be that "<span>A. Access to rivers and railroads was needed to get manufactured goods to markets," since the factories tended to be very far away from major consumer cities. </span>
In a market economy, the interaction of supply and demand determines the quantity and equilibrium price of the goods and services traded. Likewise, the market is responsible for the distribution of income through the possession of productive factors (capital, labor, etc.). In a market economy, the key signals are prices, which indicate the relative scarcity of resources.