The answer is D
A good way to remember this is to think about America before or pre-columbus, who came to the americas in 1492.
B, European settlers were immune to such diseases like smallpox because it came from their region, when knowledge that the native Americans were not immune and the disease was lethal to them, they started distributing blankets and clothing items that were infected with the viruses and caused a major impact on native population
The answer is c it is a renewable energy