Question

Edwin Chindongo became addicted to opioids when the doctor prescribed Percocet for ongoing leg pain, the result of nerve damage caused by diabetes. An opioid addiction occurs via pathways involving opioid receptors. These membrane-bound receptor proteins first bind to opioids and then send a signal to various locations in the body. First determine with what types of biomolecules these opioid receptor proteins are likely closely associated while embedded within the cell membrane. Then sort the following according to whether the membrane-bound opioid receptors are closely associating and interacting with that type of biomolecule while embedded within the cell membrane Items (5 items) (Orat and drop into the appropriate area below) Upids Sugars Fatty acids Amino acids Proteins Categories Interacts with receptor Does Hot interace Dandro

Answer 1

Opioid receptors interact with G proteins and arrestin. In consequence, opioid receptors interact with protein biomolecules.

Proteins and opioid receptors

Proteins are fundamental biomolecules composed of long chains of building blocks called amino acids linked by peptide bonds.

Proteins may have both structural (e.g., components of the cytoskeleton) and enzymatic functions (in this case, activation of signaling pathways).

Opioid receptors interact outside the cell membrane with opioid drugs (e.g., heroin) and with the G proteins inside the cell.

Opioid receptors also interact inside the cell with a special protein that is known as arrestin, thereby activating specific signaling pathways.

Learn more about opioid receptors here:

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