Question

If this is an autosomal recessive disorder, of the following individuals, which is not an obligate carrier?.

Answer 1

Answer:

III-6

Explanation:

Obligate carriers, or obligate heterozygotes, are those individuals that may be unaffected clinically, but must possess a copy of the mutant gene. For autosomal recessive conditions, obligate carriers can be the offspring of a parental mating of two carriers (50% of offspring will also be carriers). They can also be produced by a parental mating of a carrier by an affected individual (50% of offspring will be carriers).