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julsineya [31]
2 years ago
7

Does eteplirsen work for all dmd patients

Biology
1 answer:
Gemiola [76]2 years ago
4 0

Answer:

Eteplirsen is not a cure for DMD, but this medicine may lessen muscle weakness and muscle wasting caused by this disease. Eteplirsen was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some children responded to this medicine.

Explanation:

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The electron transport chain transfers electrons from donors to acceptors via redox reactions (i.e., where reduction and oxidation occur together), and couples the transfer of electrons with proton transfer (H+ ions) across the membrane. In the electron transport chain, the electrons are transferred from NADH dehydrogenase NADH to oxygen (O2) through a series of transmembrane complexes: NADH-Q oxidoreductase, Q-cytochrome c oxidoreductase and cytochrome c oxidase. In the first place, the reduced form of coenzyme Q (ubiquinone) transports the electrons from the NADH-Q oxidoreductase to the Q-cytochrome c oxidoreductase complex (Cytochrome b-c1 complex). Second, the cytochrome c transports the electrons from this complex (i.e., Cytochrome b-c1 complex) to the Cytochrome oxidase complex, this being the last component in the electron transport chain that is responsible to catalyze the reduction of O2.

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