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garri49 [273]
2 years ago
11

6. Evolution explains how variations can lead to changes in a species

Biology
1 answer:
Sever21 [200]2 years ago
3 0

Answer: Evolution is the process by which populations of organisms change over generations. Genetic variations underlie these changes. as we evolve our genetic genes change because the gametes come from 2 parents and has half the DNA (23)  and thousands of years passes and if you will compare people in ancient times to now we are completely different.

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Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.

Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.

However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.

meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.

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Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.

Learn more about breast cancer here : brainly.com/question/6747562

#SPJ4

4 0
2 years ago
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the answer is dormant

7 0
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