Question

Scott’s pimples result from the inflammatory response generated in his hair follicles. The statements below describe events that occur during this response.
Place the following statements in the chronological order that best describes the sequence of events leading to the appearance of acne.
A. P. acnes metabolized glycerol in sebum, forming free fatty acids
B. The blood vessels surrounding the follicle dilate and become more permeable
C. Immune cells such as neutrophils and phagocytes move into the follicle to try to eliminate P. acnes
D. The buuildup of dead cells, bacteria, and body fluids causes a raised pustule on the skin surface
E. Overproduction of sebum leads to an accumulation in the follicle
F. Free fatty acids stimulate the release of proinflammatory cytokines within the follicle

Answer 1

The chronological order in the sequence of acne:

• Overproduction of sebum leads to an accumulation in the follicle.
• P. acnes metabolized glycerol in sebum, forming free fatty acids.
• Free fatty acids stimulate the release of pro inflammatory cytokines within the follicle.
• The blood vessels surrounding the follicle dilate and become more permeable.
• Immune cells such as neutrophils and phagocytes move into the follicle to try to eliminate P. acnes.
• The build up of dead cells, bacteria, and body fluids causes a raised pustule on the skin surface.

Scott’s pimples result from the inflammatory response generated in his hair follicles. The above statements are the chronological order of his acne.