Answer:Loss of bone an muscle densi
Explanation:Bone loss occurs in the weightless environment of space because bones no longer have to support the body against gravity. On Earth, gravity applies a constant mechanical load to the skeletal system, that causes healthy bones to maintain a certain density so that they are able to support the body.
Answer:
Mental stress provide most change in the cardiovascular readings .
Explanation:
Mental stress -
Mental stress influences most of the change in cardiovascular system. During mental stress, the body releases cortisol and adrenaline. These are the fight hormones secreted from adrenal gland. They will increase the heart rate and blood pressure to fulfill the extra need in response to stress. Prolonged secretion of such hormone may lead to cardiovascular dysfunctions.
However, physical stress is also harmful for CVS and does make changes. but physical stress tends to get over once the activity is ceased.
Mental stress has prolonged cardiovascular risks .
The client is experiencing the stage of Anger.
Anger is an emotion characterized by antagonism toward someone or something you feel has deliberately done you wrong. Anger can be a good thing. It can give you a way to express negative feelings, for example, or motivate you to find solutions to problems. But excessive anger can cause problems.
Learn more about Anger here:
brainly.com/question/1177448
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Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
