Answer:
There are four principles at work in evolution—variation, inheritance, selection and time. These are considered the components of the evolutionary mechanism of natural selection.
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Answer:
Aspirin works by inhibiting the production of prostaglandins. Aspirin inhibits the formation of prostaglandins by combining with the COX enzymes. Prostaglandins function as messenger molecules to monitor different physiological procedures in distinct regions of the body. One of the prime activities of prostaglandins is to stimulate inflammation and pain.
Prostaglandins are also the essential controller of platelet aggregation. By changing the COX enzymes inside the platelets, aspirin makes platelets to lose the stickiness, which is required to instigate clotting of blood.
There are two forms of cyclooxygenase, that is, COX-1 and COX-2. COX-1 generates prostaglandins and COX-2 mediates pain and swelling in response to tissue injury. Aspirin prevents both COX-1 and COX-2 functioning, while COX-2 is the therapeutic target of the drug.
However, it is the association of aspirin with COX-1 in the gastrointestinal tract, which results in the unwanted side effects of the drug. COX-1 is required to sustain a thick lining of the stomach. As aspirin inhibits the COX-1 enzyme, thus, the continuous use of the drug can result in the thinning of mucus, which safeguards the stomach from gastric juices.
In such cases, stomach bleeding, ulcers, and in certain situations perforation of the stomach can take place. Therefore, aspirin exhibits both bad and good effects.
<span>The nurse should take the client to a private area preferably the client's room and help him get dressed. The client may be too erratic and confused to put the clothes on by himself or herself, so the nurse should help. The nurse does not need to be aggressive or mean because they do not want to risk agitating the client.</span>