Answer:
C. or E. One of the two. I could be wrong. Forgive me if I am.
Explanation:
An interjection can be more than one word
The question that leaves Brutus sleep-deprived at the beginning of Act 2 is when he asks Lucius what day it was. It made him awake thinking about his plan to kill Caesar. He thinks that the leader as become corrupt and unreliable.
I believe the answer might be D. Hope this helps!!! Sorry if it doesn't!