First pass metabolism of a drug is said to occur when the concentration of a drug that is administered orally is significantly reduced before it reaches the systemic circulation.
First pass metabolism usually occur in the liver.
The routes of drug administration that avoid complete first pass metabolism are: sublingual, transdermal, rectal and inhalation.
<span>This behavior is an example of B. overproduction. The frog lays thousands of eggs, which is much more than it needs, or would need in perfect conditions. However, most of those eggs doesn't survive, and little frogs are never born in that case. This is why it has to have a lot of eggs so as to ensure that a decent number of offspring survives so as to continue the species.</span>
Answer:
Is the benefit worth the cost?
Explanation:
Environmental policies application has to lead to some economic cost.
When coming up with this policies, the effect that this policies shall have towards environmental protection shall be considered.
The cost and economic effect that this policies shall cause should also be looked at.
If a policy causes insignificant change towards environmental protection and at the same time the costs are too high, then the policy should be dropped.
If a policy has got significant impact and costs less, the it should be taken.
<span>Antibiotics work by selectively targeting the reproduction or growth of specific bacteria cells and by not attacking human DNA. Antibiotics do not, or should not, target and affect human DNA gyrases, although they should target the specific bacteria growth. The host, (human) DNA needs to remain unharmed while the bacteria does not replicate.</span>