Answer:
The active functional group of a drug is that one that has the most prominent quality of adherence to the corresponding group on the target site and this selective binding of the group gave the property of targeted therapy and action. The pharmacophore modelling is done to ensure the design success of a drug but real life circumstances are mostly unpredictable. By this specific targeted action a drug acquires the property of differentiating between healthy and infected cells. Infected cells always have something different in their functional group expression as compare the the healthy cells. This helps the drug to differentiate between them.
Answer:
Excess cholesterol and a lack of ATP inhibit the activity of HMG-CoA reductase in the liver to decrease cholesterol synthesis
Answer:
The purpose of restriction enzymes are to recognize and cut the DNA to produce fragments, called restriction fragments.
I’m pretty sure the answer is C. A change in the course of a River
Answer: All of the above (I, II, III, IV)
Explanation:
The Insulin receptor is a large protein that binds to insulin and passes its message into the cell. When insulin binds to the receptor, it causes a change in shape that is propagated inside the cell, which results to MAPK activation, which regulates gene expression via Fos, Jun and Myc, PI3K activation leading to an increase in glucose transport, High affinity binding of SH2 domains to phosphorylated tyrosines and Autophosphorylation resulting in activation of tyrosine kinase.