The causes of the plague where people living in filth, not bathing and living with rats. The reason why it only spread as far as it did is because other religions that whereby Christian, bathed ritually. The effects of the plague where mass hysteria, famine, isolation and illness.
Hitler lived in the Führer Headquarters, of which there were 14. He spent more time at the Berghof, in Obersalzberg, than he did at any other place during World War II. However, he spent his final days at the Führerbunker in Berlin, where he killed himself.
The answer is Manifest Destiny. Although it can be referred to as the Westward Expansion.