An example of a missense mutation in a protein-encoding gene would most likely be a neutral mutation is option B: replacement of a polar amino acid with another polar amino acid at the protein's surface.
A frequent and well-known example of a missense mutation is the blood condition sickle-cell anemia. Missense mutations exist in the DNA at a single location in sickle-cell anemia patients. A different amino acid is required in this missense mutation, which also alters the overall structure of the protein. Similarly, replacement of a polar amino acid by another polar Ami no acid at the protein's surface is a missense mutation causing change in a single site.
A neutral mutation is one whose fixation is unrelated to natural selection. Therefore, the independence of a mutation's fixation from natural selection can be used to define the selective neutrality of a mutation.
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Complete question is:
Which example of a missense mutation in a protein-encoding gene would most likely be a neutral mutation?
a) Replacement of a polar amino acid with a nonpolar amino acid at the protein's outer surface
b) Replacement of a polar amino acid with another polar amino acid at the protein's surface
c) Replacement of a polar amino acid with another polar amino acid in the protein's interior
d) Replacement of a polar amino acid with a nonpolar amino acid in the protein's interior
Answer:
Alcohol fermentation
Explanation:
When oxygen availability is low, the cell can't perform aerobic respiration to breakdown glucose. Instead, anaerobic respiration must be performed. This occurs in cells which consume large amounts of energy, such as muscle cells. Anaerobic respiration produces much less energy than aerobic respiration
One type of anaerobic respiration formed by yeast is called alcohol fermentation (also called ethanol fermentation). This begins with glycolysis, where one molecule of glucose is broke down into 2 molecules of pyruvate. The energy from this reaction generates 2 molecules of ATP, and converts NAD+ to NADH.
Then, the two molecules of pyruvate are further broke down into 2 acetaldehydes (releasing two molecules of carbon dioxide as a by-product). These two molecules of acetaldehyde are then converted into tw molecules of ethanol, using the H ions from NADH, converting it back to NAD+. See the attached picture
This process is taken advantage of to brew beer and wine.
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