Individuals with glucose-6-phosphate dehydrogenase deficiency have increased resistance to malaria because the parasite does not survive well in cells with oxidative stress.
<h3>What is the link between G6P deficiency and malaria?</h3>
- Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked recessive disorder.
- G6PD protects cells from oxidative damage especially the RBCs whose main function is to carry oxygen.
- Mutation in the gene results in G6PD deficiency leading to oxidative stress which can lead to anemia (iron deficiency) as there is breakdown of RBCs.
- However, G6PD deficiency is quite common in parts of Africa, Middle East, and South Asia, which are the regions of high malaria endemism.
- This is due to natural selection in which G6PD deficiency is not eliminated from the population as it can protect people from malaria infection.
- Malaria parasite <em>Plasmodium</em> species does not survive well in cells with oxidative stress.
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It is called THERAPEUTIC INDEX. Therapeutic index is the comparison of the amount of a particular drug that causes the desired therapeutic effects and the amount that causes toxicity. The index can be low or high. A drug with a low therapeutic index will require only a small increase in dose to produce toxic effects in users.
Answer: In ecosystems, matter and energy are transferred from one form to another. Matter refers to all of the living and nonliving things in that environment. Nutrients and living matter are passed from producers to consumers, then broken down by decomposers. Decomposers break down dead plant and animal matter.
Explanation:
<span>In a way, the process of primordial germ line isolation encourages / supports abortions. I feel that, those who choose to terminate their pregnancies under their own consent are going to do so regardless of how their undeveloped baby is going to be utilized after the face. The process of primordial germ line isolation merely utilizes what otherwise would be waste</span>
<span>Functional traits can be shared between organisms with divergent SSU rRNA sequences because functional traits may evolve independently, be shared through horizontal gene transfer, or be lost in divergent lineages.
Functional traits are characteristics that define our behavior.
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