Whats the underlined situation
Answer:
The desire to respect the rights of citizens is what led Athens to develop the world's first democracy, as a way for people to have a say in their own government.
Explanation:
Answer:
We will explain through humanistic and neurobiological perspective
Explanation:
Humanistic perspective: Mrs B feels lonely and depressed as a result of the loss of her 82 year old Father. This has affected her teaching greatly in a negative way as she has become insecure and lonely thinking that the students don't like her too.
Neurobiological perspective: the loss of Mrs B's 82 year old father has caused chemical reactions in her brain that mean loneliness and depression. These negative emotions have left unable to concentrate on her work and as a result be disorganized.
Answer:
Abstract
Background and purpose: The sodium channel is a primary target for treating central nervous system disorders such as epilepsy. In this study the anticonvulsant effect of BmK IT2, a sodium channel-specific neurotoxin, was evaluated in different animal models of epilepsy.
Experimental approach: Experiments were performed on freely moving rats made epileptic by administration of either pentylenetetrazole (PTZ) or pilocarpine. BmK IT2 (0.05–0.5 μg in 2 μl) was microinjected into the CA1 area and its effects on PTZ-induced widespread, seizure-like behaviour and cortex epileptiform EEG, as well as on pilocarpine-induced seizure-like behaviour and c-Fos expression were studied.
Key results: Intrahippocampal application of BmK IT2 dose-dependently inhibited PTZ-induced seizure-like behaviour, and reduced the numbers and duration of the high amplitude and frequency discharges (HAFDs) of the epileptiform EEG component induced by PTZ. Similarly, in the pilocarpine-induced status epilepticus (SE) model, BmK IT2 significantly prolonged the latency to onset of the SE, reduced the severity of SE and suppressed hippocampal c-Fos expression during SE.
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