The first and foremost would be <span>the Himalayas, located south of china. The second would be the </span><span>Huang He River, located North of China.</span>
The city of troy controlled the trade routes between the aegean and black seas.
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here's a PDF that explain this topic.
In 165 AD "The Plague" rocked the Roman World was called smallpox.
The Antonine Plague of 165 to 180 AD (Plague of Galen) was the first known pandemic impacting the Roman Empire. It is believed that it was contracted and spread by soldiers who were returning from campaigns in the Near East.
The plague may have claimed the life of a Roman emperor, Lucius Verus. Scholars believe that the plague is smallpox.
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William Bradford wrote the story of Plymouth and was the second governor