The belief that "There is no god but God, and Muhammad is the Messenger of God" is central to Islam. This phrase, written in Arabic, is often prominently featured in architecture and a range of objects, including the Qur'an, Islam's holy book of divine revelations.
It seems as though as long as USA interests are left alone, nothing much would be done. Or if foreign involvement is bothering US interest then action will be taken as a last resort.