At least 2 years of medical coding experience
Answer:
Drug-drug interactions (DDIs) are one of the commonest causes of medication error in developed countries, particularly in the elderly due to poly-therapy, with a prevalence of 20-40%. In particular, poly-therapy increases the complexity of therapeutic management and thereby the risk of clinically important DDIs, which can both induce the development of adverse drug reactions or reduce the clinical efficacy. DDIs can be classify into two main groups: pharmacokinetic and pharmacodynamic. In this review, using Medline, PubMed, Embase, Cochrane library and Reference lists we searched articles published until June 30 2012, and we described the mechanism of pharmacokinetic DDIs focusing the interest on their clinical implications.
Keywords: Absorption, adverse drug reaction, distribution, drug-drug interactions, excretion, metabolism, poly-therapy
The relationship of of Gregor's family with each other are not nice, they are full of stress and pain and disdain.
<u>Explanation:</u>
The connections in the Samsa family unit are characterized by strain and disdain. Prior to his transformation, Gregor is the main working relative. Gregor's mom attempts to shield him once in a while, however she surrenders to her better half's outrage.
Gregor's change into a creepy crawly goes about as an illustration for his human life. His family treats him like a useless bug; they compel him to help them through working an extremely requesting activity as a business explorer.
