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Answer:
For each glucose that enters glycolysis, <u>2 </u>acetyl CoA enter the citric acid cycle.
Explanation:
<u>SYNTHESIS OF 2Acetyl CoA -:</u>
The glucose is transformed into 2pyruvate (6 carbon molecules are converted into 2 -3 carbon molecules) during glycolysis. In both aerobic and anaerobic respiration, glycolysis occurs frequently. This process takes place in the cytoplasm (it does not require oxygen or mitochondria), but if both oxygen and mitochondria are present, two molecules of pyruvate join mitochondria and prepare for citric acid cycle.
Until entering this, the molecules go through a mechanism known as the linked (connects glycolysis with citric acid cycle) reaction, in which the pyruvate molecule is transformed into 2 acetyl CoA (meaning 3 carbon molecules are converted into 2 carbon molecules) and a carbon molecule is released in the form of (waste product).
2NAD+ and NADH are synthesized in the linked reaction, implying that reducing power is produced. It means that electrons from pyruvate are released in the form of hydrogen, which 2NAD+ accepts and reduces to form 2 NADH.
→
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<u>Linked reaction is also known as oxidative -dicarboxylation.</u>
Hence, 2 Acetyl CoA is required to enter citric acid cycle.