I am sure that the answer is D
What do you mean by responsible? Do you want to know the genetics behind it, what the surface markers do, or why they are metically important? I think I can help.
Answer – Extrapolation
Extrapolation is the estimation of a value or quantity beyond
a known data range based on a trend in the data<span> (in other words, deducing
unknown values from trends in the known data). While extrapolating, one </span>would
usually estimate the unknown data with the presumption that
existing trends in the known data will continue or that a current method will
remain applicable.
It looks correct to me. Good job