The macromolecule responsible for storing information in organisms in DNA and it is made up of sugar, nitrogenous base (adenine, Guanine, cytosine and thymine) and phosphate group
The blank could be filled in with humerus since it is the longest bone in the leg.
It is Harmful because if the organism is used to their environment and something changes your body is not going to function right
In my opinion mixed layers would be the best choice