DNA ligases close nicks in the phosphodiester backbone of DNA. Biologically, DNA ligases are essential for the joining of Okazaki fragments during replication, and for completing short-patch DNAsynthesis occurring in DNA repair process. There are two classes of DNA ligases.
The brain is a part of the central nervous system together with the spinal chord.
The other part of the nervous system is the peripheral nervous system which is consisted of nerves and ganglions.
Humans own their ability of speech to the three areas in the brain.
Broca's area is essential for forming words, Wernicke's area helps us understand the meaning of words and the arcuate fasciculus connects these two areas and gives speech coherence.