Adenylate cyclases (ACs) are the membrane-bound glycoproteins that convert ATP to cAMP and pyrophosphate.
When activated by G-protein Gs, adenylate cyclases (ACs), which are membrane-bound glycoproteins, catalyze the synthesis of cAMP from ATP.
Different AC isoforms are widely expressed in various tissues that participate in regulatory systems in response to particular stimuli.
Humans have 9 different AC isoforms, with AC5 and AC6 thought to be particularly important for cardiac activities.
Nitric oxide has an impact on the activity of AC6, hence the protein's nitrosylation may control how it works. However, little is known about the structural variables that affect nitrosylation in ACs and how they relate to G's.
We predict the cysteines that are prone to nitrosylation using this 3D model, and we use virtual ligand screening to find potential new AC6 ligands.
According to our model, the AC-Gs interface's Cys174 in G's and Cys1004 in AC6 (subunit C2) are two potential residues that could experience reversible nitrosylation.
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Answer:
During platelet plug formation, platelets begin to stick to: collagen with the assistance of von Willebrand factor. As a platelet plug forms at an injury site platelets become activated and their cytoplasm: degranulates as they release chemicals such as ADP and thromboxane A2.
Explanation:
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The question is correct but the option is incorrect. The correct option is as follows:
a) Expedited Review b) Not Human Subjects c) Convened Review d) Exempt Review e) Full board review.
Answer:
Full board review.
Explanation:
IRB ( Institutional Review Board) is mainly responsible for the protection and maintains the ethics that are involved in the research related to humans and other animals.
The full board review requires more time that n the other type of review. This review is mainly done in the cases where the participants can get misleading information. This review includes the research that are based on to involve the judgement and involves less risk. The information given in the question explain the full board type review.
Thus, the correct answer is full board review.
Answer:
Theophrastus is known as the 'father of botany'.
Explanation:
