Answer:
1. Inhibiting IP3 channels, leading to decreased Ca2 in the sarcoplasm and reduced contraction.
2. Increasing the relative activity of MLCP, leading to a decrease in tension.
3. Activating K channels, increasing K leaking out of the cell which hyperpolarizes it and decreases the likelihood of Ca2 entry.
Explanation
In smooth muscle, cyclic AMP (cAMP) mediates relaxation because cAMP inhibits a specific kinase required for myosin light chain protein (MLCP) phosphorylation, thereby triggering contraction in the smooth muscles. It has been shown that cAMP inhibits 1,4,5-trisphosphate (IP3)-dependent calcium ions (Ca 2+) release by activation of the cGMP-dependent protein kinase (PKG). PKG proteins act to modulate Ca2+ oscillations by stimulating sarcoplasmic Ca2+-ATPase membrane proteins, increasing Ca2+ in the sarcoplasmic reticulum stores and Ca2+ efflux from the cells, and activate voltage-gated potassium (K) channels, thereby leading to membrane hyperpolarization and reducing Ca2+ entry through Ca2+ channels.
It is known as a transgenic organism. This procedure is otherwise called "genetic engineering." Genes of one species can be altered, or qualities can be transplanted starting with one animal types then onto the next. Genetic engineering is made conceivable by recombinant DNA innovation. Living beings that have modified genomes are known as transgenic.
<span>Suffocation is a most leading reason of death in grain storage
bins. Grain handling industry is a high hazard industry where workers can be
exposed to numerous serious and life threatening hazards. These hazards
include: fires and explosions from grain dust accumulation, suffocation from
engulfment and entrapment in grain bins, falls from heights and crushing
injuries and amputations from grain handling equipment. </span>
Answer:
the steps are
we need to keep tight security system in forest area
hunting of animal must be stopped
Answer:
p53 helps the cells from passing on mutations that lead to DNA damage. Hence, it is known as the guardian angel of the cell as it helps fight against cancer. However, if p53 becomes defective or missing, then the mutations will lead to cancer.
Mutations in the p53 can also cause the tumor-suppressing genes to convert into tumor causing genes. Hence, mutations in such kind of genes can be very harmful for the body.
