Question

A person who has type AB blood and is heterozygous for Rh factor has children with a person who is heterozygous for type A blood and is negative for Rh factor. List all possible gametes these two individuals could produce and list the genotype and phenotype ratios of the F1 generation.

Answer 1

Blood type is determined by the alleles coding for the antigen present on cell membranes.

The person with type AB blood has a heterozygous Rh factor.

• Half the gametes have Rh factor (+) and the other half are negative for Rh factor (-)
• Half the gametes have IA and the other half have IB
• The possible gamete combinations are IA+, IA-, IB+, IB-

The person with heterozygous type A blood is negative for Rh factor

• All gametes are negative for Rh factor (-)
• Half the gametes have IA and the other half have IO
• The possible gametes are IA-, IO-

The genotype ratio is 1:1:1:1:1:1:1:1

The phenotype ratio is 2: 2:1:1:1:1.

Learn more about blood types here:

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