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Answer:
GUA and GUG.
Explanation:
If you look at the attached genetic code, the wild-type glutamic acid (Glu) is coded by the codons GAA and GAG.
Valine (Val) can be coded by the codons GUU, GUC, GUA or GUG.
Sickle-cell hemoglobin arises from a single mutation, which causes the translation of Val instead of Glu. The only codons that code for Valine that differ in just one base with the Glu codons are GUA and GUG.
