Nutrition is what help us grow and repair, nutrition has nutrients like water, minerals, and vitamins.
<span>The nurse will most likely observe Paget's disease on the client's medical chart. Paget's disease interferes with the body's bone tissue recycling process and results in increased blood flow around affected bones, flushing extra alkaline phosphatase and urinary hydroxyproline from the body.</span>
<span>Lafora disease is the most severe teenage-onset progressive epilepsy, a unique form of glycogenosis with perikaryal accumulation of an abnormal form of glycogen, and a neurodegenerative disorder exhibiting an unusual generalized organellar disintegration. The disease is caused by mutations of the EPM2A gene, which encodes two isoforms of the laforin protein tyrosine phosphatase, having alternate carboxyl termini, one localized in the cytoplasm (endoplasmic reticulum) and the other in the nucleus. To date, all documented disease mutations, including the knockout mouse model deletion, have been in the segment of the protein common to both isoforms. It is therefore not known whether dysfunction of the cytoplasmic, nuclear, or both isoforms leads to the disease. In the present work, we identify six novel mutations, one of which, c.950insT (Q319fs), is the first mutation specific to the cytoplasmic laforin isoform, implicating this isoform in disease pathogenesis. To confirm this mutation's deleterious effect on laforin, we studied the resultant protein's subcellular localization and function and show a drastic reduction in its phosphatase activity, despite maintenance of its location at the endoplasmic reticulum.
I got my information from </span>https://www.ncbi.nlm.nih.gov/pubmed/14722920
Climate changes thats what im guessing .. not too sure though ... sorry
Answer:
Addition used for 'either or' events , Multiplication used for 'and' events
Explanation:
Addition is used when Probability is of 'one event <u>or</u> other event'
Multiplication is used when Probability is of 'one event & other event'
Ex : Probability of A winning = 0.4
Probability of B winning = 0.3
Probability (A or B winning) = 0.4 + 0.3 = 0.7
Probability (A & B winning) = 0.4 x 0.3 = 0.12
