A group of Chinese women with PCOS who were receiving treatment saw several metabolic and hormonal imbalances improve after taking BBR. The primary consequences may be connected to the modifications in body composition in obesity and dyslipidemia. For the evaluation of the possible beneficial metabolic effects of BBR in women with PCOS, additional controlled trials are required.
PCOS:
- Objective: Insulin resistance is a common metabolic and reproductive condition called polycystic ovarian syndrome (PCOS) (IR). A quinoline derivative alkaloid known as berberine (BBR) has been utilized as an insulin sensitizer and is isolated from Chinese medicinal herbs. There may be a therapeutic benefit for PCOS from BBR. The purpose of this study was to compare the effects of BBR and metformin (MET) on the metabolic characteristics of PCOS-affected women.
- Design and methods: Ninety nine PCOS and IR patients were randomly assigned to one of three therapy groups: BBR+ compound cyproterone acetate (CPA;
), MET
CPA
, and placebo CPA 
for 
months. Before and after the treatment period, metabolic and hormonal measures as well as the clinical characteristics of the women were evaluated. - Results: Reduced waist circumference, waist-to-hip ratio (WHR;P<
), total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDLC; P<
), as well as increased levels of high-density lipoprotein cholesterol (HDLC) and sex hormone-binding globulin (SHBG; P<) were all observed following treatment with BBR as compared to MET. Similarly, BBR treatment decreased WHR, fasting plasma glucose, fasting insulin, homeostasis model evaluation for IR, area under the insulin curve, TC, LDLC, and TG (P<), while increasing HDLC and SHBG (P<) as compared to placebo.
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<u>Answer</u>:
"It increases the mutation rate" is an advantage of sexual reproduction
<u>Explanation</u>:
The basic thing of evolution is fundamental, as it helps in generation of genetic variation on which the selection can act. Sexual reproduction leads to genetic diversity, and this genetic diversity leads to increase the mutation rate. Genetic diversity occurs because of two various cells which are combining together and biological assortment which happens at the time of cell division. Neutral genetic diversity in the population leads to high mutation rate.
Answer:
Parasympathetic nervous system
Explanation:
Parasympathetic nervous system (PNS) along with sympathetic nervous system (SNS) makes autonomic nervous system (ANS). ANS controls the functioning of internal processes like digestion rate, heart rate, respiratory rate etc. During a threat or stressful situation SNS is activated. It increases heart rate, respiratory rate and directs blood flow towards peripheral muscles as a part of "fight or flight response". When the situation becomes normal, PNS is activated which restores all the vitals as a part of "rest and digest" mechanism.
Since here Byron almost got into an accident, he was scared a lot due to which his SNS was activated. Eventually when he realized that he is out of danger, his PNS got activated which returned his heart rate and blood pressure to normal levels.
The alkali metals in group l of the periodic table all have a single electron in the outermost shell. These metals form covalent bonds with for example the halogens, which have 7 electrons in their outer shell.
When the alkali metal halide, such as KCl is dissolved in water, it dissociates into ions. The K atom loses the single electron, and therefore has a positive charge. In turn, the chloride atom gains the electron and becomes the negatively charged chloride ion.
