1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
andreev551 [17]
2 years ago
13

A 67-year-old man was found to have a plasma calcium level of 12.2 mg/dL during a follow-up visit. The man had a 3-year history

of Hodgkin lymphoma. He was recently diagnosed with nephrolithiasis for which he had been treated with hydrochlorothiazide forthe past 3 weeks. Which of the following best explains the most likely mechanism of thiazideinduced hypercalcemia?
a. Activation of the Na+/Ca2+ exchanger in the distal tubule
b. Increased Ca2+ reabsorption in the proximal tubule
c. Decreased secretion of parathyroid hormone
d. Decreased renal excretion of vitamin D
e. Activation of Na+/K+/2Cl− symporter in the thick ascending loop of Henle
f. Increased glomerular filtration of Ca2+
Health
1 answer:
Zigmanuir [339]2 years ago
4 0

Activation of the Na+/Ca2+ exchanger in the distal tubule is the most likely mechanism of thiazide hypercalcemia

Thiazide-hypercalcemia is a well-known clinical condition. By inhibiting the thiazide-sensitive NaCl transporter in the distal convoluted tubule, which is closely related to calcium transport, thiazides cause an increase in sodium excretion.

Thiazides hypercalcemia decreases urine calcium levels while raising blood calcium levels via promoting calcium reabsorption from the luminal membrane into the interstitium in exchange for sodium. High calcium levels are a well-known adverse effect of thiazide hypercalcemia diuretics including hydrochlorothiazide (Microzide) and chlorthalidone, which are used to treat high blood pressure. By blocking calcium from being discharged in the urine, which can also result in kidney stones, these drugs can boost calcium levels.

To learn more about Thiazides hypercalcemia please visit -
brainly.com/question/10279749
#SPJ4

You might be interested in
Legal drug abuse can’t cause physical harm or dependence
madam [21]
Very false. Thousands of people all around the world that get in some kind accident or have medical issues ans or have a surgery for any reason. And need medications to recover, and end up addicted even after the treatment is over. And depend on the pills even after all the side effects of pain or whatever it may be is gone. Thousands on thousands of people are effected by this every year its a big issue.
4 0
3 years ago
What kind of solution occurs in your mouth when you eat something with a high salt content?
babunello [35]
The solution that occurs in your mouth when you eat foods with a high salt content is called a hypertonic solution. This will make the correct answer C. 
6 0
3 years ago
Which of the following is NOT a good exercise for the lower body?
klasskru [66]
The answer is B. Spine stretch

Spine stretch is an exercise to stretch your back bone, which mean your upper body, not the lower one.

NB :
Hip Flexor : To stretch your thigh
Calf stretch & Harmstring stretch : To stretch your lower legs
8 0
4 years ago
Read 2 more answers
Compare your body’s response to antigen “a” both times you were exposed. describe at least two ways in which the body’s response
Elanso [62]
Most likely your body won't be as harmed the 2nd time due to the preparation of your cells. 
6 0
3 years ago
STIs are a major cause of ______.
ioda
Human papillomavirus (HPV) causes genital warts. It is also a very common STI in Canada, especially among teens and young adults. Research shows that the virus that causes genital warts is also linked to cervical cancer. Syphilis is a bacterial infection that is less common but still remains a cause for concern.. So C
8 0
4 years ago
Read 2 more answers
Other questions:
  • Bioenergetics tells us that our bodies are filled with unseen energy<br> true or false?
    9·2 answers
  • What is a characteristic of a bed bug
    6·1 answer
  • How did you solve business problems during the early years of your business operation ?
    11·1 answer
  • How does Alcoholics Anonymous help people deal with alcoholism?
    10·1 answer
  • Schizophrenia is a mental disorder where the sufferer can have delusions, hallucinations, disorganized thinking, an inability to
    15·1 answer
  • What is the correct definition for puberty
    11·2 answers
  • What challenges do you think doctors encounter when they try to diagnose patients with symptoms that are common to different pat
    10·1 answer
  • Which of the following is an example of an external influence?
    15·2 answers
  • Tom Brady and the Buccaneers or Patrick Mahomes and the Chiefs?
    6·1 answer
  • Grandma falls to the floor. She is holding her left arm, is having difficulty breathing, and says her chest hurts. What should y
    10·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!