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spayn [35]
2 years ago
13

Chemotherapy in adult highgrade glioma: a systematic review and metaanalysis of individual patient data from 12 randomized trial

s
Mathematics
1 answer:
daser333 [38]2 years ago
4 0

Systemic chemotherapy's impact on survival and recurrence in people with high-grade glioma has not been conclusively studied.

<h3>What is Systemic chemotherapy?</h3>

Patients undergoing systemic chemotherapy can get their chemotherapy drugs intravenously or orally. The medication may be injected into the body intravenously, or through an IV, or intramuscular, into a muscle (IM).

Some Key features of systemic chemotherapy are-

  • Background: In order to evaluate the effects of such treatment on survival and recurrence, we conducted a systematic review and meta-analysis.
  • Methods: From 12 randomised controlled studies, information on 3004 patients was incorporated (11 published and one unpublished).
  • Findings: Overall, the findings indicated a significant survival extension associated with chemotherapy, with a hazard ratio of 0.85 (95 percent confidence interval [CI] 0.78–0.91, p0.0001) or a relative reduction in mortality risk of 15%. There was no proof that a patient's age, gender, histology, performance status, or degree of resection affected how chemotherapy worked in any particular way.
  • Interpretation: Further research into pharmacological treatment for malignant tumors is encouraged by this modest but noticeable improvement in survival from chemotherapy.

To know more about Chemotherapy, here

brainly.com/question/1033035

#SPJ4

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The following 5 questions are based on this information: An economist claims that average weekly food expenditure of households
liq [111]

Answer:

Null hypothesis:\mu_{1}-\mu_{0}\leq 0

Alternative hypothesis:\mu_{1}-\mu_{2}>0

SE=\sqrt{\frac{12.5^2}{35}+\frac{9.25^2}{30}}=2.705

b) 2.70

t=\frac{(164-159)-0}{\sqrt{\frac{12.5^2}{35}+\frac{9.25^2}{30}}}=1.850

b. 1.85

p_v =P(Z>1.85)=0.032

b. 0.03

a. We can reject H(0) in favor of H(a)

Step-by-step explanation:

Data given and notation

\bar X_{1}=164 represent the mean for the sample 1

\bar X_{2}=159 represent the mean for the sample 2

\sigma_{1}=12.5 represent the population standard deviation for the sample 1

s_{2}=9.25 represent the population standard deviation for the sample B2

n_{1}=35 sample size selected 1

n_{2}=30 sample size selected 2

\alpha=0.05 represent the significance level for the hypothesis test.

t would represent the statistic (variable of interest)

p_v represent the p value for the test (variable of interest)

State the null and alternative hypotheses.

We need to conduct a hypothesis in order to check if the expenditure of households in City 1 is more than that of households in City 2, the system of hypothesis would be:

Null hypothesis:\mu_{1}-\mu_{0}\leq 0

Alternative hypothesis:\mu_{1}-\mu_{2}>0

We know the population deviations, so for this case is better apply a z test to compare means, and the statistic is given by:

z=\frac{(\bar X_{1}-\bar X_{2})-0}{\sqrt{\frac{\sigma^2_{1}}{n_{1}}+\frac{\sigma^2_{2}}{n_{2}}}} (1)

t-test: "Is used to compare group means. Is one of the most common tests and is used to determine whether the means of two groups are equal to each other".

Standard error

The standard error on this case is given by:

SE=\sqrt{\frac{s^2_{1}}{n_{1}}+\frac{s^2_{2}}{n_{2}}}

Replacing the values that we have we got:

SE=\sqrt{\frac{12.5^2}{35}+\frac{9.25^2}{30}}=2.705

b. 2.70

Calculate the statistic

We can replace in formula (1) the info given like this:

t=\frac{(164-159)-0}{\sqrt{\frac{12.5^2}{35}+\frac{9.25^2}{30}}}=1.850  

P-value

Since is a one side right tailed test the p value would be:

p_v =P(Z>1.85)=0.032

b. 0.03

Conclusion

If we compare the p value and the significance level given \alpha=0.05 we see that p_v so we can conclude that we have enough evidence to reject the null hypothesis.

a. We can reject H(0) in favor of H(a)

4 0
3 years ago
Rewrite the subtraction as addition 3- (-10)
Bumek [7]
<span>Rewrite the subtraction as addition 3- (-10)

= 3 + 10</span>
4 0
3 years ago
Which matrix is equal to
just olya [345]

Answer:

L

O

+

65.91828182

Step-by-step explanation:

6 0
3 years ago
Read 2 more answers
If the first 4 terms of an infinite geometric sequence are 150, 120, 96, and 76.8, then the sum of all the terms in the sequence
hammer [34]

The sum of the sequence is 750

<h3>How to determine the sum of the series?</h3>

The series is given as:

150, 120, 96, and 76.8,

Start by calculating the common ratio using:

r = T2/T1

This gives

r = 120/150

r = 0.8

The sum of the series is then calculated as:

S = \frac{a}{1 - r}

This gives

S = \frac{150}{1 - 0.8}

Evaluate

S = 750

Hence, the sum of the sequence is 750

Read more about sequence at:

brainly.com/question/6561461

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4 0
2 years ago
Leah's house has a media room with a large flat-screen television to watch movies. The media room television has a width of 8 fe
Naddik [55]
The Answer Would Be 64 because if you divide 8/4.5 its equal to 64/36.
8 0
3 years ago
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