Uncapping enzymes promote degradation from the 3' end of the mRNA, whereas phosphorylation occurs in serine, threonine, and tryptophan and activates/deactivates.
<h3>What is phosphorylation?</h3>
Phosphorylation is a posttranslational modification of proteins in which a phosphate group is added by specific protein enzymes called kinases.
Phosphorylation can both activate and deactivate a protein depending on the specific substrate that is phosphorylated.
Moreover, Double stranded RNA with one strand that is complementary to a portion of the mRNA you want to degrade is most efficient at promoting mRNA degradation.
In conclusion, uncapping enzymes promote degradation from the 3' end of the mRNA, whereas phosphorylation occurs in serine, threonine, and tryptophan and activates/deactivates.
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