Question

A nurse assisting a nursing student with medications asks the student to describe how penicillins (PCNs) work to treat bacterial infections. The student is correct in responding that penicillins: Group of answer choices disinhibit transpeptidases inhibit autolysins. disrupt bacterial cell wall synthesis inhibit host cell wall function

Answer 1

Penicillins disrupts bacterial cell wall synthesis.

How does penicillin affect bacterial cell walls?

• Penicillin kills bacteria by inhibiting the proteins which cross-link peptidoglycans in the cell wall .
• When a bacterium divides in the presence of penicillin, it cannot fill in the “holes” left in its cell wall.
• β-Lactam antibiotics, including penicillins, cephalosporins, monobactams, and carbapenems, are distinguished by a lactam ring in their molecular structure and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls.
• Penicillins work by bursting the cell wall of bacteria. Drugs in the penicillin class work by indirectly bursting bacterial cell walls.
• They do this by acting directly on peptidoglycans, which play an essential structural role in bacterial cells.

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