During a 12-hour fast in a human, the first macro-molecule to get depleted is typically a <u>glycogen</u>.
<h3>What is a
glycogen?</h3>
In biology study, it means the large & branched polysaccharide that is the main storage form of glucose in animals and humans. It serves as an important energy reservoir when energy is required by the body, glycogen in broken down to glucose, which then enters the glycolytic or pentose phosphate pathway or is released into the bloodstream.
Hence, as the Glycogen is also an important form of glucose storage in fungi and bacteria, it is the first macromolecule to get depleted during a 12-hour fast in a human.
Read more about glycogen
brainly.com/question/4303062
#SPJ1
