Question

How does the glycolysis reaction catalyzed by GAPDH from T. tenax differ from the reaction carried out in E. coli?

Answer 1

The difference between the glycolysis reaction catalyzed by GAPDH from T. tenax and by E. coli is that the catalysis by T. tenax forms 3-phosphoglycerate instead of 1, 3-bisphophoglycerate (formed by E. coli catalysis).

Glycolysis is the process of cellular respiration which is common in both aerobic as well as anaerobic organisms. It occurs in the cytoplasm of cell. In glycolysis, breakdown of glucose occurs to form 2 molecules of pyruvate.

GAPDH is the short form for the enzyme Glyceraldehyde-3-Phosphate Dehydrogenase. It is involved in catalyzing the a reaction in glycolysis. The reaction involves the simultaneous phosphorylation and oxidation of glyceraldehyde-3-phosphate to 1,3-biphosphoglycerate.

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