Answer:
Sickle cell disease is due to a type of substitution mutation.
Explanation:
Sickle cell disease is a condition that is transmitted from parents to children in an autosomal recessive inheritance pattern. It is due to a mutation that is capable of altering the shape of the erythrocyte, as well as its ability to circulate and carry oxygen.
The mutation that occurs in sickle cell disease is due to an alteration in the β-chain of hemoglobin, caused by the substitution of thymine base by adenine in the DNA that determines it. As a result, valine replaces glutamic acid in the β-chain amino acid sequence, with the consequences described.
- <em>The other options are not correct because </em><u><em>deletion, duplication and translocation </em></u><em>correspond to chromosomal mutations, not responsible for sickle cell disease.</em>
Answer:
The DNA mutation causes a change in the amino acid sequence for hemoglobin, which causes a change in the shape of red blood cells.
Explanation:
Sickle cell anemia is one of a group of disorders known as sickle cell disease. Sickle cell anemia is an inherited red blood cell disorder in which there aren't enough healthy red blood cells to carry oxygen throughout your body.
Normally, the flexible, round red blood cells move easily through blood vessels. In sickle cell anemia, the red blood are shaped like sickles or crescent moons. These rigid, sticky cells can get stuck in small blood vessels, which can slow or block blood flow and oxygen to parts of the body.
Sickle cell anemia is caused by a mutation in the gene that tells your body to make the iron-rich compound that makes blood red and enables red blood cells to carry oxygen from your lungs throughout your body (hemoglobin). In sickle cell anemia, the abnormal hemoglobin causes red blood cells to become rigid, sticky and misshapen.
The sickle cell mutation reflects a single change in the amino acid building blocks of the oxygen-transport protein, hemoglobin. This protein, which is the component that gives red cells their color, has two subunits. The alpha subunit is normal in people with sickle cell disease. The beta subunit has the amino acid valine at position 6 instead of the glutamic acid that is normally present. The alteration is the basis of all the problems that occur in people with sickle cell disease.
The populations of the species there will go extinct
Answer:
no it is not possible
Explanation:
bc when you do a punnett square brown hair is dominant so there is not a possible way for their child to have blonde.
