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marusya05 [52]
1 year ago
12

Pancreatic Enzyme Supplements Are Not Effective for Relieving Abdominal Pain in Patients with Chronic Pancreatitis: Meta-Analysi

s and Systematic Review of Randomized Controlled Trials.
Medicine
1 answer:
Anastaziya [24]1 year ago
6 0

Despite minimal evidence of effectiveness, pancreatic enzyme supplementation is frequently used to relieve pain in people with chronic pancreatitis.

Comparing pancreatic enzyme supplementation to placebo, no improvement in discomfort was seen. The only trial that used enzymes without an enteric coating did indicate a decrease in pain score. In both analyses, there was a significant amount of study heterogeneity. A random model meta-analysis of three studies found no evidence of a difference between the periods of administering pancreatic enzyme supplementation versus placebo in the mean daily pain score (mean difference: 0.09 (1.57-1.39), p=0.91) or average weekly analgesic consumption (mean difference: 0.30 (2.37-1.77), p=0.77). Given their high cost and probable adverse effects, pancreatic enzyme supplements shouldn't be recommended only for treating abdominal pain in people with chronic pancreatitis.

Learn more about chronic pancreatitis here:-

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The most appropriate step to manage the patient's symptoms as mentioned in question is Quadriceps strengthening exercises.

<h2>What is quadriceps?</h2>

The Quadriceps femoris is one of the largest and most powerful muscle of the human body. The quadriceps femoris is both a hip flexor and a knee extensor. It is made up of  four individual muscles; the rectus femoris, and three vastus muscles.  They are one of the strongest muscles in the body and make up the majority of the thigh.

Anterior knee discomfort in young women is frequently caused by patellofemoral pain syndrome. Usually, chronic usage or misalignment is at blame for such discomfort. A patellofemoral compression test can simulate the discomfort. Exercises for stretching and strengthening of quadriceps are part of the initial therapy, along with activity modification and non-steroidal anti-inflammatory medications.

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