Background- In patients with intracranial artery stenosis, a long-term advantage of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) for the prevention of recurrent stroke has not been proven. We studied patients with intracranial arterial stenosis who were enrolled in the Cilostazol Stroke Prevention Study for Antiplatelet Combination trial, a randomized controlled trial in high-risk Japanese patients with ischemic stroke, to compare the efficacy and safety of DAPT with cilostazol and clopidogrel or aspirin to those of SAPT with clopidogrel or aspirin. Techniques and Outcomes In patients with ischemic stroke with symptomatic or asymptomatic intracranial arterial stenosis of at least 50% in a major intracranial artery, we compared the vascular and hemorrhagic events between DAPT and SAPT.
Patients were divided into two groups: 275 were given DAPT, while 272 were given SAPT. In contrast to SAPT, which had a higher risk of serious or life-threatening bleeding, DAPT had a lower risk of ischemic stroke (hazard ratio [HR], 0.47; 95% CI, 0.23-0.95); and a composite of stroke, myocardial infarction, and vascular mortality (HR, 0.48; 95% CI, 0.26-0.91). Conclusions In patients with intracranial artery stenosis following stroke, DAPT using cilostazol was superior than SAPT using clopidogrel or aspirin for the prevention of recurrent stroke and vascular events without raising bleeding risk.
<h3>What is
stroke?</h3>
When anything prevents blood flow to a portion of the brain or when a blood artery in the brain bursts, a stroke, also known as a brain attack, happens. The brain either ages or suffers harm in both scenarios. A stroke may result in permanent brain damage, chronic disability, or even fatality.
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Answer:
decrease, increase
Explanation:
Most people in the US need to <u>decrease </u>their sodium intake and <u>increase </u>their potassium intake to meet recommendations for a healthy diet.
124 gtt/min drops per minute should the nurse regulate the infusion . Because Sodium nitroprusside (nipride) 50 mg is mixed in d5w 250 ml.
182/2.2 Equals 82.73 kg when converting from lbs to kg. For this client, determine the dosage: 413.65 mcg/min = 5 mcg x 82.73. Calculate how much mcg Sodium nitroprusside are present in 1 ml: 200 mcg per ml is 250/50,000 mcg.
The customer is to receive 2.07ml per minute (413.65 mcg/min x 200 mcg/ml), or 413.65 mcg/min x 200 mcg/ml. When the drip factor is 60 gtt/ml, the equation is 60 2.07 = 124.28 gtt/min OR, when utilising dimensional analysis, the equation is 60 gtt/ml X 250 ml/50 mg X 1 mg/1,000 mcg X 5 mcg/kg/min X 1 kg/2.2 pounds X 182 lbs.
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Answer:
High Blood Pressure. Hypertension increases one’s risk of cardiovascular disease as the blood vessel walls become irritated by the increased pressure exerted by the blood flowing through. As more and more damage is done to the vessel walls, plaque tends to form, in turn increasing the likelihood of atherosclerosis and coronary heart disease.
Answer:
Liquid and Tablet,
For a liquid medicine you have to drink it, for a tablet medicine you have to drink it with water.
Liquid medicine example: Anthony throat was not feeling all right so he drank some medicine.
Tablet medicine example: Anthony had a headache so he took a tablet.
Explanation:
