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Andrew [12]
2 years ago
6

cytochrome p450 enzymes contribute to the metabolism of lsd to nor-lsd and 2-oxo-3-hydroxy-lsd: implications for clinical lsd us

e
Biology
1 answer:
MrRissso [65]2 years ago
3 0

Implications for clinical LSD use: Cytochrome P450 enzymes participate in the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD. This cell-based (in vitro) study examined the possibility for clinical LSD usage and the role of the cytochrome P450 (CYPs) enzymes in the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD.

This cell-based (in vitro) study examined the possibility for clinical LSD usage and the role of the cytochrome P450 (CYPs) enzymes in the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD. The study discovered that multiple CYPs significantly contributed to the process even though the human liver only converted a little amount of LSD to nor-LSD and O-H-LSD. According to the review, there is a connection between genetic polymorphisms and pharmacological interactions, which may have an impact on the pharmacodynamics and pharmacokinetics of LSD. Additionally, it was discovered that O-H-LSD is inactive whereas nor-LSD may have inactive hallucinogenic effects similar to that of LSD.

Learn more about metabolism brainly.com/question/1966475

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